Monday, February 6, 2012

Precision BioSciences Announces Allowances in Fifth and Sixth U.S. Patent Applications Related to Engineered Meganucleases

CED Member Precision BioSciences, Inc., a leader in the field of genome engineering, today announced that the United States Patent and Trademark Office (PTO) has issued Notices of Allowance for U.S. Patent Applications 13/246,270 and 13/246,346 (“the '270 and ‘346 Applications”). The allowed claims relate to an assortment of genome engineering methods, including the use of defined engineered meganucleases in isolated human cells. These methods constitute an important aspect of Precision’s genome engineering technology known as the Directed Nuclease Editor or DNE.

“We are pleased that the PTO has now allowed these claims, which cover methods utilized for cleaving target DNA sites in isolated human cells”
The allowance of the claims of the '270 and ‘346 Applications follow Precision’s recently allowed claims from U.S. Patent Applications 13/246,380, 13/245,607, and 13/245,596 and further augments Precision’s ability to protect its proprietary DNE technology, features of which are already covered under claims of Precision’s U.S. Patent No. 8,021,867 (“the '867 Patent”). Precision announced in October 2011 that it has asserted the '867 Patent against Cellectis SA in a lawsuit pending in the U.S. District Court for the Eastern District of North Carolina.
“We are pleased that the PTO has now allowed these claims, which cover methods utilized for cleaving target DNA sites in isolated human cells,” stated Mike Nicholson, Precision BioSciences’ Director of Cell Biology. “Issuance of these allowed patent applications, along with our other recently allowed applications will provide Precision with what we believe is the strongest U.S. patent estate related to engineered meganucleases.”
About Precision BioSciences
Precision BioSciences’ mission is to continually provide, improve, and enable the world’s most powerful genome engineering technology. Precision’s proprietary Directed Nuclease EditorTM (DNE) technology enables the production of genome editing enzymes that can insert, remove, modify, and regulate essentially any gene in mammalian or plant cells.
Precision BioSciences’ vision is to be the conduit through which the world’s greatest genome engineering challenges are solved. Precision has successfully utilized its DNE technology to create innovative products in partnerships with many of the world’s largest biopharmaceutical, agbiotech, and animal research firms. Internally, Precision is developing applications of DNE in biological production and human therapeutics. For additional information, please visit